IGCSE · Biology 0610 · Reproduction

Reproduction in humans: IGCSE Biology questions with answers

Free Reproduction in humans questions for IGCSE Biology (0610), part of Reproduction. Each question has the answer and the marking points an examiner would look for.

Generate a full Reproduction in Humans worksheet →All Reproduction questions

Reproduction in humans practice questions

Question 1Multiple choice · 1 markA* challenge

Where do fertilisation and implantation take place in humans?

fertilisationimplantation
Auterus lininguterus lining
Buterusoviduct
Coviductuterus lining
Dovaryuterus lining
Show answer

Answer: C

Question 2Multiple choice · 1 mark

Which structure produces sperm?

  1. A testes
  2. B urethra
  3. C sperm duct
  4. D prostate gland
Show answer

Answer: A

Question 3Structured · 5 marksA* challenge

The female reproductive system produces eggs.

(a)

Name the site of fertilisation.

[1]
(b)

State the function of the placenta.

[2]
(c)

Explain why the blood of the mother and the fetus do not mix.

[2]
Show answers and mark scheme
PartAnswer and marking pointsMarks
(a)oviduct
oviduct B1
1
(b)exchange of nutrients, oxygen, waste
exchange of oxygen and nutrients to the fetus B1
removal of carbon dioxide and urea B1
2
(c)different pressure/blood groups; barrier to toxins/pathogens
Any 2 of: prevents high maternal blood pressure damaging the fetus; acts as a barrier to some pathogens and toxins; blood groups may differ B2
2
Question 4Structured · 12 marks

This question is about human reproduction.

(a)

State where fertilisation takes place and what is formed.

[2]
(b)

Give two ways in which a sperm cell is adapted for its function.

[2]
(c)

Describe the functions of the placenta.

[3]
(d)

Explain why the blood of the mother and fetus do not mix.

[2]
(e)

Describe the roles of oestrogen and progesterone in the menstrual cycle.

[3]
Show answers and mark scheme
PartAnswer and marking pointsMarks
(a)oviduct; zygote
in the oviduct B1
a zygote is formed B1
2
(b)flagellum to swim; many mitochondria; acrosome enzymes
Any 2 of: flagellum for swimming; many mitochondria to release energy; acrosome containing enzymes to digest a way into the egg B2
2
(c)exchange of oxygen, nutrients to fetus; removes CO₂ and urea; barrier to some pathogens; secretes hormones
Any 3 of: oxygen and nutrients diffuse from mother to fetus; carbon dioxide and urea diffuse from fetus to mother; acts as a barrier to some pathogens / toxins; produces hormones (progesterone) B3
3
(d)different blood groups could clot; mother’s higher pressure could damage fetus
the blood groups may be different and could clot B1
the mother’s blood pressure is higher and could damage the fetus’s blood vessels B1
2
(e)oestrogen repairs uterus lining; progesterone maintains lining; fall in progesterone leads to menstruation
oestrogen causes the uterus lining to thicken / repair B1
progesterone maintains the uterus lining B1
a fall in progesterone causes the lining to break down (menstruation) B1
3
Question 5Structured · 12 marks

This question is about the human reproductive systems and hormones.

(a)

State the functions of the testes and the ovaries.

[2]
(b)

Describe two secondary sexual characteristics in males and two in females, caused by sex hormones at puberty.

[4]
(c)

Name the hormone that triggers ovulation and the gland that secretes it.

[2]
(d)

Describe how the combined contraceptive pill prevents pregnancy.

[2]
(e)

Explain why a condom reduces the spread of HIV, but the combined contraceptive pill does not.

[2]
Show answers and mark scheme
PartAnswer and marking pointsMarks
(a)produce sperm and testosterone; produce eggs and oestrogen/progesterone
testes produce sperm and testosterone B1
ovaries produce eggs and oestrogen (and progesterone) B1
2
(b)male: deeper voice, facial hair, muscle; female: breasts, hips widen, menstruation
Any 4 of: males: voice deepens; facial / body hair; increased muscle growth; females: breasts develop; hips widen; menstruation begins (two for each) B4
4
(c)LH; pituitary gland
LH (luteinising hormone) B1
pituitary gland B1
2
(d)contains oestrogen and progesterone; inhibits FSH/LH, no ovulation
contains oestrogen and progesterone B1
which inhibit FSH / LH secretion so eggs are not released B1
2
(e)barrier prevents exchange of body fluids; pill is not a barrier
a condom is a barrier that prevents exchange of body fluids / semen containing the virus B1
the pill is not a barrier, so body fluids containing HIV are still exchanged B1
2
Question 6Structured · 4 marks

During pregnancy the fetus develops in the uterus.

(a)

State the function of the amniotic fluid.

[1]
(b)

State the function of the umbilical cord.

[1]
(c)

Explain why a pregnant woman should not smoke.

[2]
Show answers and mark scheme
PartAnswer and marking pointsMarks
(a)protects fetus from mechanical shock
protects the fetus against mechanical shock B1
1
(b)joins fetus to placenta
connects the fetus to the placenta (carries blood) B1
1
(c)CO and nicotine cross placenta; low birth mass
carbon monoxide/nicotine cross the placenta B1
reducing oxygen supply/growth (low birth weight) B1
2

More Reproduction questions

Want a mentor, not just a paper?

Riyaz Shaikh has mentored IGCSE, IB and A Level students for 15+ years, one-on-one, online and in Mumbai. The hardest questions on this site are the ones he uses to find a student's weak points.

Meet Riyaz →

Original Cambridge-style practice questions written for mentorriyaz.in. These are not Cambridge past paper questions, and this site is not affiliated with or endorsed by Cambridge University Press & Assessment. Updated 2026-11-04. Paper generator · mentorriyaz.in