IGCSE Biology (0610) topical questions with answers
Every IGCSE Biology topic, with free past-paper-style questions and full mark schemes. Pick a chapter to practise its questions, or generate a complete 0610-format paper in seconds, from easy warm-ups to A*-level "brutal" papers.
Paper 1 · Multiple Choice (Core · 40 questions · 45 min); Paper 2 · Multiple Choice (Extended · 40 questions · 45 min); Paper 3 · Theory (Core · structured questions); Paper 4 · Theory (Extended · structured questions); Paper 6 · Alternative to Practical (Core & Extended · 4 questions, Q4 = planning).
Sample IGCSE Biology questions
A mixed set from across the syllabus. Questions marked A* challenge come from the hardest bank.
Question 1Multiple choice · 1 markA* challenge
Which row matches the cell structure with its function?
ribosome
mitochondrion
cell wall
A
protein synthesis
aerobic respiration
controls what enters the cell
B
protein synthesis
aerobic respiration
prevents the cell bursting
C
aerobic respiration
protein synthesis
prevents the cell bursting
D
protein synthesis
photosynthesis
controls what enters the cell
Show answer
Answer: B
Question 2Structured · 4 marksA* challenge
A car moves, uses fuel and gives out waste gases, but it is not alive.
(a)
Explain why a car is not a living organism, using two characteristics of life.
[2]
(b)
Define excretion.
[2]
Show answers and mark scheme
Part
Answer and marking points
Marks
(a)
cannot grow or reproduce; no sensitivity
it cannot reproduce B1 it cannot grow (or respond to stimuli by itself / no cells) B1
2
(b)
removal of waste products of metabolism and excess substances
removal of the waste products of metabolism (toxic materials) B1 and substances in excess of requirements B1
2
Question 3Structured · 12 marks
A student places potato cylinders, each of initial mass 2.50 g, in sucrose solutions of different concentrations for 1 hour, then reweighs them.
sucrose concentration / mol/dm³
0.0
0.2
0.4
0.6
0.8
final mass / g
2.80
2.65
2.45
2.27
2.13
Table 3.1
(a)
Define osmosis.
[2]
(b)
Calculate the percentage change in mass at 0.8 mol/dm³.
[2]
(c)
Explain why the potato in 0.0 mol/dm³ gained mass.
[3]
(d)
Explain why percentage change in mass is used rather than change in mass.
[1]
(e)
Estimate the concentration of sucrose that has the same water potential as the potato cells. Explain your answer.
[2]
(f)
Describe the appearance of a plant cell placed in a concentrated sugar solution, and explain why.
[2]
Show answers and mark scheme
Part
Answer and marking points
Marks
(a)
net movement of water through partially permeable membrane from dilute to concentrated solution
net movement of water molecules from a region of higher water potential (dilute solution) to lower water potential (concentrated solution) B1 through a partially permeable membrane B1
2
(b)
−15.0%
(2.13 − 2.50)/2.50 × 100 M1 −15.0% A1
2
(c)
water potential higher outside; water enters by osmosis; cells become turgid
water potential of the water is higher than in the potato cells B1 water enters the cells by osmosis through the partially permeable membrane B1 cells become turgid B1
3
(d)
cylinders may differ in starting mass; allows comparison
to allow comparison when the starting masses are different B1
1
(e)
about 0.35 mol/dm³
about 0.35 mol/dm³ B1 where there is no change in mass (no net movement of water) B1
2
(f)
plasmolysed: membrane pulls away from wall; water leaves vacuole by osmosis
cell becomes plasmolysed / flaccid with the cytoplasm pulling away from the cell wall B1 water leaves by osmosis B1
2
Question 4Structured · 6 marks
Teeth are involved in mechanical digestion.
(a)
Describe the functions of incisors and molars.
[2]
(b)
Explain how tooth decay is caused.
[3]
(c)
Explain why mechanical digestion speeds up chemical digestion.
[1]
Show answers and mark scheme
Part
Answer and marking points
Marks
(a)
incisors cut/bite; molars grind
incisors: cutting and biting B1 molars: grinding/chewing B1
2
(b)
bacteria feed on sugar, produce acid, dissolves enamel
bacteria in plaque feed on sugars B1 produce acid B1 acid dissolves the enamel B1
3
(c)
larger surface area for enzymes
it increases the surface area for enzymes to act on B1
1
Question 5Structured · 3 marks
A cheek cell has an actual diameter of 20 µm. It is viewed with a microscope at a magnification of ×400.
(a)
Calculate the diameter of the image in mm.
[2]
(b)
State why micrometres are used to measure cells.
[1]
Show answers and mark scheme
Part
Answer and marking points
Marks
(a)
8 mm
image = actual × magnification = 8000 µm C1 8 mm A1
2
(b)
cells are very small
Any 1 of: cells are very small; micrometres give convenient numbers B1
1
Question 6Structured · 3 marks
The lungs are protected from pathogens and particles.
(a)
Describe the role of mucus and cilia.
[2]
(b)
Explain why the trachea has rings of cartilage.
[1]
Show answers and mark scheme
Part
Answer and marking points
Marks
(a)
mucus traps; cilia sweep up
mucus traps pathogens and dust B1 cilia beat to move the mucus up to the throat B1
2
(b)
keeps airway open
to keep the airway open during breathing B1
1
Frequently asked questions
Are these real 0610 past paper questions?
No. They are original questions written to match the IGCSE Biology 0610 syllabus and the style of real Cambridge papers, so you can practise beyond the past papers you have already done.
Do the Biology questions have answers?
Yes. Every question on these pages has its answer, and every generated paper comes with a full Cambridge-style mark scheme you can download as a PDF.
Can I make a full IGCSE Biology practice paper?
Yes. Choose the paper (Paper 1 Multiple Choice, Paper 2 Multiple Choice, Paper 3 Theory, Paper 4 Theory, Paper 6 Alternative to Practical), the topics, the marks and the difficulty, and the generator builds a fresh paper with the same number and style of questions as the real exam.
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Original Cambridge-style practice questions written for mentorriyaz.in. These are not Cambridge past paper questions, and this site is not affiliated with or endorsed by Cambridge University Press & Assessment. Updated 2026-11-04. Paper generator · mentorriyaz.in